Al Meena received his education in different countries, including the United States, Britain and Pakistan. He attended the St. Patrick's College in Karachi and graduated with a degree in journalism from the University of Karachi.
Al Maeena began his career in 1972, joining the Saudi Arabian Airlines (Saudia) as an intern. He worked at several positions in the airline including as chief editor of Saudi World. In 1982, he became the editor-in-chief of Arab News. Al Maeena was one of four journalists to cover the resumption of diplomatic ties between Saudi Arabia and Russia in 1990. He left his post in 1993, becoming the CEO of the Saudi Public Relations Company (SPRC), a position he held for five years. He returned to the top editor's post at Arab News in 1998 and continued until October 2011.
He was appointed editor-in-chief of Saudi Gazette on 2 April 2012. Almaeena occasionally contributes commentary columns for Gulf News, Al Eqtisadiah, Times of Oman, Asian Age, The China Post, Asharq Al-Awsat, Al Madina and Urdu News. He was also a Saudi television news anchor, talk show host, radio announcer and lecturer. Khaled Almaeena also serves as a Member of Advisory Board for Gulf at TAIB Bank.
Al Maeena is a veteran Arabian journalist. He is reported to be close to King Fahd and King Abdullah. He is also considered to have close relations with then-Riyadh governor Prince Salman. The late Ahmad Ibn Salman was very fond of him. The other sons of Prince Salman including Faisal bin Salman had also close relations with him.
Al Maeena was honored with the highest civilian award Sitara-e-Pakistan in 2008 by the Pakistan government.